Seth Harlem is the Co-Founder and Chief Executive Officer of Thema Brain Health, a Boca Raton, Florida-based healthcare company specializing in the early detection and prevention of cognitive decline and Alzheimer’s disease. Under his leadership, Thema has introduced innovative tools such as ApoE Aware, an at-home genetic test that assesses Alzheimer’s risk and provides personalized prevention plans through telehealth consultations.

Harlem co-founded Thema Brain Health in 2022 alongside Dr. Robert Colton, a seasoned healthcare entrepreneur known for establishing MDVIP and ClearlyDerm. Their collaboration aims to shift the paradigm in cognitive healthcare by emphasizing proactive monitoring and intervention, akin to managing chronic conditions like hypertension or diabetes.

Prior to Thema, Harlem served as CEO of Taithera, Inc., a nanomedicine company focused on bone-targeted drug delivery for musculoskeletal conditions and bone cancers. His entrepreneurial journey includes participation in ELabNYC, a competitive life sciences accelerator program, where he honed his expertise in healthcare innovation.

In recognition of his contributions to healthcare, Harlem was named one of SCALE Healthcare’s Top 60 Most Influential Leaders in 2025.

Through his ventures, Harlem continues to advocate for integrating technology and personalized care to enhance patient outcomes in cognitive health.