Dr. James Weber is the founder and Chief Executive Officer of GI Alliance, the largest independent gastroenterology practice network in the United States. Under his leadership, GI Alliance has expanded to encompass over 800 physicians across more than 400 locations nationwide, delivering comprehensive, patient-centered digestive health care.

Dr. Weber’s medical journey began with a degree in Biomedical Science from Texas A&M University, followed by a medical degree from the University of Texas Southwestern Medical School in Dallas. He completed his residency in internal medicine at Parkland Memorial Hospital and a gastroenterology fellowship at Baylor University Medical Center.

In 1995, Dr. Weber founded Texas Digestive Disease Consultants (TDDC), which grew to become the nation’s largest gastroenterology group under his leadership. TDDC was the first practice to join GI Alliance when it was established in 2018.

Beyond his executive roles, Dr. Weber is an active clinician specializing in inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis. He continues to see patients at GI Alliance’s Lone Star Endoscopy in Southlake, Texas.

Dr. Weber also serves as President and Board Chair of the Digestive Health Physicians Association (DHPA), a national advocacy organization representing over 2,300 gastroenterologists. He is affiliated with several professional societies, including the American Gastroenterological Association, the American College of Gastroenterology, and the American Society for Gastrointestinal Endoscopy.

Recognized for his contributions to the field, Dr. Weber has received accolades such as “Doctor of the Year” from the Crohn’s and Colitis Foundation of North Texas, and has been named among the “Best Doctors in Dallas” by D Magazine and “Top Doctors in Tarrant County” by Fort Worth Magazine.

Through his visionary leadership, Dr. Weber has advanced GI Alliance’s mission to provide high-quality, physician-led, and patient-first gastroenterology care across the nation.